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Bowen's disease
Bowen's disease (BD) (also known as "squamous cell carcinoma in situ"〔James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. ISBN 0-7216-2921-0.〕) is a neoplastic skin disease; it can be considered as an early stage or intraepidermal form of squamous cell carcinoma. It was named after John T. Bowen. (Erythroplasia of Queyrat is a particular type of squamous cell carcinoma in situ which can arise on the glans or prepuce in males and vulva in females, and may be induced by HPV〔J Invest Dermatol 2000 Sep;115(3):396-401〕). It is reported to occur in corneoscleral limbus.〔Syed Imtiaz Ali Shah, Saeed Ahmed Sangi, Seraj Ahmed Abbasi: Bowen’s Disease: Pak J Ophthalmol 1998 Vol. 14, No. 1.p.37-38.〕
==Causes==
Causes of BD include solar damage, arsenic, immunosuppression (including AIDS), viral infection (human papillomavirus or HPV), chronic skin injury, and other dermatoses.
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